Watch for increased sleepiness or decreased breathing when starting LYRICA or LYRICA CR or when the dose is increased. Watch for increased sleepiness or decreased breathing when starting LYRICA or when the dose is increased. LYRICA may cause serious, even life-threatening, allergic reactions. Stop taking LYRICA and call your doctor right away if you have any signs of a serious allergic reaction. Some signs are swelling of your face, mouth, lips, gums, tongue, throat, or neck, if you have any …